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An AAV capsid reprogrammed to bind human transferrin receptor mediates brain-wide gene delivery

05/2024 Journal: Science Author: Qin Huang., Ken Y.Chan., Jason Wu.,et al

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Clathrin-associated AP-1 controls termination of STING singalling

10/2022 Journal: Nature Author: Liu, Y., Xu, P., Rivara, S., et al

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SARS-CoV-2 Delta and Omicron variants evade population antibody response by mutations in a single spike epitope

09/2022 Journal: Nature Microbiological Author: He, P., Liu, B., Gao, X., et al

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Publication

Metabolic pathway assembly using docking domains from type I cis-AT polyketide synthases

09/2022 Journal: Nature Communication Author: Sun, X., Yuang, Y., Chen, Q., et al

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Publication

Cryo-EM structures and binding of mouse ACE2 to SARS-CoV-2 variants of concern

08/2022 Journal: bioRxiv Author: Ni, D., Turelli, P., Beckert, B., et al

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Theranostic application of 64Cu/177Lu-labeled anti-Trop2 monoclonal antibody in pancreatic cancer tumor models

08/2022 Journal: European Journal of Nuclear Medicine and Molecular Imaging Author: Li, C., Liu, J., Yang, X., et al

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PI(4,5)P2-stimulated positive feedback drives the recruitment of Dishevelled to Frizzled in Wnt–β-catenin signaling

07/2022 Journal: ScienceSignaling Author: Mahoney, J., Bruguera, E., Vasishtha, M., et al.

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Tumor necrosis factor alpha delivers exogenous inflammation-related microRNAs to recipient cells with functional targeting capabilities

07/2022 Journal: Molecular Therapy Author: Zhao, Y., Zhang, T., Shen, X., et al.

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magazine

Breaking the Status Quo of Characterization with Biolayer Interferometry

06/2022 Magazine: LifeScience Review

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Publications

A Class of Shark-Derived Single-Domain Antibodies can Broadly Neutralize SARS-Related Coronaviruses and the Structural Basis of Neutralization and Omicron Escape

05/2022 Journal: Small Method Author: Feng, B., Chen, Z., Sun, J., et al.

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Publications

An automated, rapid fluorescent immunoassay to quantify serum soluble programmed death-1 (PD-1) protein using testing-on-a-probe biosensors

05/2022 Journal: Clinical Chemistry and Laboratory Medicine Author: Zhang, J., Chen, L., Xu, Q., et al.

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publications

Development of a rapid neutralizing antibody test for SARS-CoV-2 and its application for neutralizing antibody screening and vaccinated serum testing

04/2022 Journal: Infectious Medicine Author: Li, Y., Wang, M., Wu, H., et al.

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publications

Broad neutralization of SARS-CoV-2 variants by an inhalable bispecific single-domain antibody

04/2022 Journal: Cell Author: Li, C., Zhan, W., Yang, Z., et al.

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publications

Lipid nanoparticle-encapsulated mRNA antibody provides long-term protection against SARS-CoV-2 in mice and hamsters

04/2022 Journal: Nature Author: Deng, YQ., Zhang, N., Zhang, Y., et al.

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publications

Measurements of SARS-CoV-2 antibody dissociation rate constant by chaotrope-free biolayer interferometry in serum of COVID-19 convalescent patients

03/2022 Journal: Biosensors and Bioelectronics Author: Hao, Y., Yang, H., Karbaschi, M., et al.

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publications

First-in-class trispecific VHH-Fc based antibody with potent prophylactic and therapeutic efficacy against SARS-CoV-2 and variants

03/2022 Journal: Clinica Chimica Author: Titong, A., Gallolu Kankanamalage, S., Dong, J. et al.

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publications

Reconstitution of purified membrane protein dimers in lipid nanodiscs with defined stoichiometry and orientation using a split GFP tether

01/2022 Journal: JBC Author: Bruguera, E., Mahoney, J., Weis, W., et al.

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publications

Structural analysis of the Spike of the Omicron SARS-CoV-2 variant by cryo-EM and implications for immune evasion

12/2021 Journal: bioRxiv Author: Ni, D., Lau, K., Turelli, P., et al.

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publications

Development of recombinant COVID-19 vaccine based on CHO-producted, prefusion spike trimer and alum/CpG adjuvants

10/2021 Journal: Vaccine Author: Liu, H., Zhou, C., An, J., et al.

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publications

Predicting Mutational Effects on Receptor Binding of the Spike Protein of SARS-CoV-2 Variants

10/2021 Journal: Journal of the American Chemical Society Author: Bai, C., Wang, J., Chen, G., et al.

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publications

Generation and Characterization of a Nanobody Against SARS-CoV

09/2021 Journal: Virologica Sinica Author: Li, JF., He, L., Deng, YQ. et al.

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publications

TOP-Plus is a Versatile Biosensor Platform for Monitoring SARS-CoV-2 Antibody Durability

09/2021 Journal: Clinical Chemistry Author: Racine-Brzostek, S., Karbaschi, M., Gaebler, C., et al.

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publications

Surface Ligand Valency and Immunoliposome Binding: when More Is Not Always Better

08/2021 Journal: Pharm Res Author: Li, H., Di, J., Peng, B. et al.

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publications

Lack of blocking activity in anti-CTLA-4 antibodies reduces toxicity, but not anti-tumor efficacy

07/2021 Journal: bioRxiv Author: Stone, E., Carter, K., Wagner, E., et al.

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publications

Potent RBD-specific neutralizing rabbit monoclonal antibodies recognize emerging SARS-CoV-2 variants elicited by DNA prime-protein boost vaccination

06/2021 Journal: Emerging Microbes & Infections Author: Chen, Y., Zhu, L., Huang, W., et al.

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publications

Germline IGHV3-53-encoded RBD-targeting neutralizing antibodies are commonly present in the antibody repertoires of COVID-19 patients

05/2021 Journal: Virologica Sinica Author: Li, J., He, L., Deng, Y., et al.

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publications

A SARS-CoV-2 Label-Free Surrogate Virus Neutralization Test and a Longitudinal Study of Antibody Characteristics in COVID-19 Patients

04/2021 Journal: JCM Author: Luo, R., Yun, C., Chakraborty, I., et al.

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publications

Development of humanized tri-specific nanobodies with potent neutralization for SARS-CoV-2

10/2020 Journal: Scientific Reports Author: Dong, J., Huang, B., Wang, B., et al.

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publications

A potent SARS-CoV-2 neutralizing human monoclonal antibody that reduces viral burden and disease severity in Syrian hamsters

09/2020 Journal: Frontiers in Immunology Author: Fagre, A. C., Manhard, J., Adams, R., et al.

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publications

Selection and characterization of an ssDNA aptamer against thyroglobulin

09/2020 Journal: Talanta Author: Zhu, C., Li, L., Fang, S., et al.

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publications

Kinetics of SARS-CoV-2 Antibody Avidity maturation and association with disease severity

09/2020 Journal: Clinical Infectious Diseases Author: Luo, R., Chakraborty, I., Yun, C., et al.

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publications

Development of Label-Free Immunoassays as Novel Solutions for the measurement of monoclonal antibody drugs and antidrug antibodies

07/2020 Journal: Clinical Chemistry Author: Luo, R., Chakraborty, I., Lazar-Molnar, E., et al.

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publications

Development of multi-specific humanized llama antibodies blocking SARS-CoV-2/ACE2 interaction with high affinity and avidity

05/2020 Journal: Emerging Microbes & Infections Author: Dong, J., Huang, B., Jia, Z., et al.

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publications

LegoBody: facile generation of bispecific and multi-specific antibodies

12/2019 Journal: bioRxiv Author: Lang, S., Yang, S., Bidlingmaier, S., et al.

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publications

A thin-film interferometry-based label-free immunoassay for the detection of daratumumab interference in serum protein electrophoresis

12/2019 Journal: Clinica Chimica Author: Luo, R., Chakraborty, I., Zuk, R., et al.